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Clostridium difficile infection (CDI) in health care settings and in the community poses major clinical and economic issues. It can lead to recurrent infections, chronic diarrhea, and has been the source of outbreaks in both acute and long-term care facilities.
Current treatment options for recurrent CDI, usually consisting of antibiotics, are limited as 60% of patients will experience multiple episodes. An alternative to antibiotic therapy for CDI are fecal microbiota transplants (FMT), which involves infusion of healthy microbiota directly into the colon of infected patients.
FMTs combat C. difficile by reconstituting the altered colonic microbiota. The cumulative success rate of FMT for recurrent CDI is 85%. This presentation will highlight the experience of using FMT to control CDI outbreaks in an acute and a long-term care facilities in Ontario.
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Presenter: Dr. Christine Lee
Dr. Lee obtained a medical degree from the University of Toronto before completing specialty training infectious diseases and microbiology residency, also at U of T. Dr. Lee is currently a professor at McMaster University as well as a Clinical Professor at University of British Columbia. She has been researching the use of fecal transplant for C. difficile infection since 2008.
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