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Why working at PHO is important to me:

"Working at PHO presents me with a unique opportunity to implement the most recent findings in molecular biology of pathogenic microorganisms to improve public health and to support PHO’s mandate of providing scientific and technical advice for those working to protect and promote the health of Ontarians. This is only possible due to my collaboration with a wide range of professionals at the PHO: epidemiologists, medical and clinical microbiologists and technologists, health care providers in Ontario and academic researchers around the globe."

George Broukhanski, Molecular Specialist/Biologist
New: Scientist Profile
 
 
Watch Dr. George Broukhanski talk about:
  • What excites him about his work
  • The impact of his research
  • Why he chose PHO

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    Appointments

    Academic degrees and accreditations

    • Post-doctoral Fellow (Microbiology), University of Toronto
    • Post-doctoral training, Research Institute of Microbiology, Moscow, Russia
    • Doctor of philosophy (Microbiology), Research Institute of Microbiology, Moscow, Russia
    • Master of science (Genetics), Lomonosov Moscow State University, Moscow, Russia

    Areas of expertise

    • Hospital-acquired infections
    • Molecular epidemiology
    • Bacterial strains typing
    • Clostridium difficile
    • Mycobacterium tuberculosis

    PHO research interests

    • Molecular biology of pathogenic bacteria
    • Hospital epidemiology of C. difficile

    Current PHO research activities

    • Investigating biomarkers associated with C. difficile strains causing outbreaks in hospitals and developing methods for detection and typing.
    • Assessing MMLVA (Modified Multi-Locus Variable Number of Tandem Repeat Analysis) and ribotyping combination test and Whole Genome Sequencing as a replacement for PFGE (current typing method).
    • Collaborating with infection control/outbreak investigation teams at Ontario hospitals by providing results of advanced typing of C. difficile and assisting with interpretation of data.
    • Supervising of University of Toronto students doing research projects in my laboratory.
    • Supervising laboratory technologists/Ph.D. students involved in internally and externally funded (CIHR) projects on hospital epidemiology of C. difficile.
    • Presenting lectures to students at U of T and other universities as well as Toronto hospitals on molecular epidemiology of pathogens. 

    Top publications

    1. Lee CH, Belanger JE, Kassam Z, Smieja M, Higgins D, Broukhanski G, Kim PT. The outcome and long-term follow-up of 94 patients with recurrent and refractory Clostridium difficile infection using single to multiple fecal microbiota transplantation via retention enema. Eur J Clin Microbiol Infect Dis. 2014;33(8):1425-8.

    2. Jessamine PG, Desjardins M, Gillis T, Scollard D, Jamieson F, Broukhanski G, Chedore P, McCarthy A. Leprosy-like illness in a patient with Mycobacterium lepromatosis from Ontario, Canada. J Drugs Dermatol. 2012;11(2):229-33.

    3. Broukhanski G, Simor A, Pillai DR. Defining criteria to interpret multilocus variable-number tandem repeat analysis to aid Clostridium difficile outbreak investigation. J Med Microbiol. 2011;60(Pt 8):1095-100.

    4. Broukhanski G, Low DE, Pillai DR. Modified multiple-locus variable-number tandem-repeat analysis for rapid identification and typing of Clostridium difficile during institutional outbreaks. J Clin Microbiol. 2011;49(5):1983-6.

    5. Olsen CW, Karasin AI, Carman S, Li Y, Bastien N, Ojkic D, Alves D, Charbonneau G, Henning BM, Low DE, Burton L, Broukhanski G. Triple reassortant H3N2 influenza A viruses, Canada, 2005. Emerg Infect Dis. 2006;12(7):1132-5.

     

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    Page last updated: 2017-08-18 11:07 AM
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