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PHO Micro Rounds: Assessment of influenza vaccine effectiveness in the Global Influenza Hospital Study Network (GIHSN)
Monday, February 13, 2017 01:00 pm to 02:00 pm
Venue: 661 University Avenue, Boardroom 17-53
Emergency Preparedness; Laboratory Testing and Sciences; Health Promotion; Infectious Diseases
City: Toronto
Type: PHO Rounds: Microbiology
Format: In Person; Webinar
Real-time polymerase chain reaction (RT-PCR) is the current gold-standard technique for respiratory viruses screening, includinginfluenza A and B detection and strain genotyping. At FISABIO-Public Health in Valencia, Spain, they routinely perform real-time RT-PCR screening of local hospital influenza-like illness (ILI) / severe acute respiratory infection (SARI) cases to determine the viral disease burden in different patient groups. Influenza detection and typing data are used in a local case-positive control-negative Influenza Vaccine Effectiveness (IVE) study, which is later pooled with other sites within the framework of the Global Influenza Hospital Surveillance Network (GIHSN). Sequencing and molecular epidemiologyof influenza-positive hospital ILI/SARI casesfrom vaccinated and unvaccinated individuals are also performed to explore antigenic drift in detail. Finally, the potential public health impact of further improvements of molecular screening and virus sequencing (i.e. whole genome and next-generation sequencing) will be discussed.

Presenter: Dr. F. Xavier López-Labrador

F. Xavier López-Labrador is a senior investigator of Spain´s National Healthcare System. He holds an MSc and a PhD (Microbiology) from the Hospital Clinic, University of Barcelona Medical School. He completed a Postdoctoral fellowship in immunology at Stanford University Medical School. Upon his return to Spain, he held a tenure-track Investigator position at the National Healthcare System (Instituto de Salud Carlos III), first in the Microbiology Service of the La Fe University Hospital and later in the Center for Public Health Research (FISABIO-Public Health) in Valencia. He was also an Associate Professor of Microbiology at the University of Valencia. He is a member of CIBER-ESP (Spanish Network for Epidemiology and Public Health), and is also a member of the Spanish Society for Virology, Spanish Society for Clinical Microbiology, European Society for Clinical Virology and the American Society for Microbiology. His main interests are hepatotropic and, more recently, respiratory viruses.
DISCLAIMER: The opinions expressed by speakers and moderators do not necessarily reflect the official policies or views of Public Health Ontario, nor does the mention of trade names, commercial practices, or organizations imply endorsement by Public Health Ontario.
Please note that you will receive details on how to join the webinar after registering for this event.
Public Health Ontario Rounds are approved for continuing medical education from the Royal College of Physicians and Surgeons. PHO Grand Rounds are also approved by Council of Professional Experience for professional development hours (PDHs) for members of the Canadian Institute of Public Health Inspectors (CIPHI). For more information, contact
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Public Health Ontario is committed to complying with the Accessibility for Ontarians with Disabilities Act (AODA). If you require accommodations to participate in this event, please contact 647-260-7100 or

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