Détails des événements

PHO Grand Rounds: The Off-Target Effects of Antibiotics on the Human Microbiome

The human microbiome is associated with and causally implicated in numerous mucosal and systemic infectious, inflammatory, immune and neoplastic diseases, as well as responses to therapy.  Antimicrobials cause significant disruption of the microbiome and their effects on microbiome composition and function can have both transient and lasting effects for human hosts. This presentation describes the composition and functions of the human microbiome, its relationship to human disease and the impact of antimicrobials on these functions.

By the end of this session, participants will be able to:

  1. Describe the relationship between microbiome composition and function.
  2. Explain the role of intestinal anaerobes in immune homeostasis and colonization resistance to pathogens.
  3. Discuss the impact of antimicrobials on the structure and function of the intestinal microbiome.
  4. Compare various treatment strategies for protecting, or remediating antimicrobial-induced perturbation of the microbiome.

Présentateur(s): Dr. Bryan Coburn

Bryan Coburn is an Infectious Diseases Clinician-Scientist at the University Health Network and a Scientist in Advanced Diagnostics at the Toronto General Hospital Research Institute.  His laboratory studies mucosal microbiota and their interactions with host immune system function in infectious, immune and neoplastic diseases.

Avis de non-responsabilité

The opinions expressed by speakers and moderators do not necessarily reflect the official policies or views of Public Health Ontario, nor does the mention of trade names, commercial practices, or organizations imply endorsement by Public Health Ontario.


PHO Rounds are a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada (RCPSC). In order to receive written documentation for Continuing Medical Education (CME) credits, please check “Yes” beside the question “Do you require CME credits?” on the registration form.

College of Family Physicians of Canada (CFPC) Affiliate Members may count RCPSC credits toward their Mainpro+ credit requirements. All other CFPC members may claim up to 50 Certified credits per cycle for participation in RCPSC MOC Section 1 accredited activities.

PHO Grand Rounds are also approved by the Council of Professional Experience for professional development hours (PDHs) for members of the Canadian Institute of Public Health Inspectors (CIPHI).

For more information or for a record of registration for other Continuing Education purposes, please contact events@oahpp.ca


Public Health Ontario is committed to complying with the Accessibility for Ontarians with Disabilities Act (AODA). If you require accommodations to participate in this event, please contact 647-260-7100 or events@oahpp.ca.

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Publié le 1 nov. 2019