Sujets émergents : synopsis des principaux articles de recherche sur la COVID-19

SPO agit de façon proactive en surveillant, en examinant et en évaluant les recherches internationales pertinentes concernant le nouveau coronavirus (COVID-19). La présente page Web décrit brièvement et résume les points saillants des nouveaux articles qui sont importants pour la santé publique en Ontario. Elle sera mise à jour régulièrement à mesure que la situation évoluera et que d’autres rapports de recherche seront diffusés.

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Mis à jour le 19 févr. 2021

Date Posted	Reference	Brief Description	Synopsis
New February 19, 2020	Verma AA, Hora T, Jung HY, Fralick M, Malecki SL, Lapointe-Shaw L, et al. Characteristics and outcomes of hospital admissions for COVID-19 and influenza in the Toronto area. CMAJ 2021 Feb 10. [Early release. Subject to revision] Available from: https://www.cmaj.ca/content/early/2021/02/10/cmaj.202795	This study compared patient characteristics, resource use, clinical care and outcomes for 1735 adult patients with COVID-19 and influenza. The study setting was in 7 hospitals in Toronto and Mississauga, Ontario during the first wave of the pandemic.	Review of “Characteristics and outcomes of hospital admissions for COVID-19 and influenza in the Toronto area”
New February 19, 2020	Brooks JT, Beezhold DH, Noti JD, Coyle JP, Derk RC, Blachere FM, et al. Maximizing fit for cloth and medical procedure masks to improve performance and reduce SARS-CoV-2 transmission and exposure, 2021. MMWR. 2021 Feb 10 [ePub ahead of print]. Available from: http://dx.doi.org/10.15585/mmwr.mm7007e1	An experimental simulation study using masked dummy headforms was conducted using different configurations and modifications with three-ply medical masks and three-ply cotton masks to evaluate source control on a source model and protection afforded to a receiver under controlled conditions.	Review of “Maximizing fit for cloth and medical procedure masks to improve performance and reduce SARS-CoV-2 transmission and exposure, 2021”
February 16, 2021	Voysey M, Costa Clemens SA, Madhi SA, Weckx LY, Folegatti PM, Aley PK, et al. Single dose administration, and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine. Lancet 2021 Feb 01. [Epub ahead of print]. Available from: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3777268	In this pre-print study, the authors’ conclude “ChAdOx1 nCoV-19 vaccination programmes aimed at vaccinating a large proportion of the population with a single dose, with a second dose given after a 3 month period is an effective strategy for reducing disease, and may be the optimal for rollout of a pandemic vaccine when supplies are limited in the short term.”	Review of "Single dose administration, and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine"
February 2, 2021	Rapid review on the characteristics of effective non-medical face masks in reducing the risk of SARS-CoV-2 transmission [Internet]. Ottawa, ON: Public Health Agency of Canada; 2021 Jan 5 [cited 2021 Jan 27]. Available from: https://www.nccmt.ca/covid-19/covid-19-evidence-reviews/261	This rapid review examined the evidence on the characteristics and efficacy of non-medical masks in reducing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission.	Review of “Rapid review on the characteristics of effective non-medical face masks in reducing the risk of SARS-CoV-2 transmission”
January 28, 2021	Zimmerman KO, Akinboyo IC, Brookhart MA, Boutzoukas AE, McGann K, Smith MJ, et al. Incidence and secondary transmission of SARS-CoV-2 infections in schools. Pediatrics. 2021 Jan 8 [Epub ahead of print]. Available from: https://doi.org/10.1542/peds.2020-048090	This study evaluated the hypothesis that in-person learning would not lead to substantial Coronavirus Disease 2019 (COVID-19) transmission among school students and staff in North Carolina, United States, if students and staff adhere to wearing of face masks, physical distancing and hand hygiene.	Review of “Incidence and secondary transmission of SARS-CoV-2 infections in schools”
January 27, 2021	Horby P, Huntley C, Davies N, Edmunds J, Ferguson N, Medley G, et al. NERVTAG paper on COVID-19 variant of concern B.1.1.7 [Internet]. London: Crown copyright; 2021 [cited 2021 Jan 26]. Available from: https://www.gov.uk/government/publications/nervtag-paper-on-covid-19-variant-of-concern-b117	The New and Emerging Respiratory Virus Threats Advisory Group (NERVTAG) reported with 40% to 50% confidence that COVID-19 Variant of Concern (VOC) B.1.1.7 is associated with an increased risk of death compared to non-VOC, based on preliminary evidence from data of COVID-19 deaths linked to testing results in the community.	Review of “NERVTAG Paper on COVID-19 variant of concern B.1.1.7”
January 21, 2021	Rolfes MA, Grijalva CG, Zhu Y, McLean HQ, Hanson KE, Belongia EA, et al. Implications of shortened quarantine among household contacts of index patients with confirmed SARS-CoV-2 infection — Tennessee and Wisconsin, April–September 2020. MMWR Morb Mortal Wkly Rep. 2021;69(5152):1633-7. Available from: http://dx.doi.org/10.15585/mmwr.mm695152a1	This study used data from an ongoing study of household Coronavirus Disease 2019 (COVID-19) transmission in Nashville, Tennessee and Marshfield, Wisconsin to determine the proportion of household contacts with detectable virus after a shortened quarantine period.	Review of “Implications of shortened quarantine among household contacts of index patients with confirmed SARS-CoV-2 infection — Tennessee and Wisconsin, April–September 2020”
January 19, 2021	Brandal LT, Ofitserova TS, Meijerink H, Rykkvin R, Lund HM, Hungnes O, et al. Minimal transmission of SARS-CoV-2 from paediatric COVID-19 cases in primary schools, Norway, August to November 2020. Euro Surveill. 2021;26(1):pii=2002011. https://doi.org/10.2807/1560-7917.ES.2020.26.1.2002011.	This study prospectively examined transmission of severe acute respiratory coronavirus 2 (SARS-CoV-2) from confirmed paediatric cases in Norwegian primary schools between August and November 2020.	Review of “Minimal transmission of SARS-CoV-2 from paediatric COVID-19 cases in primary schools, Norway, August to November 2020”
January 11, 2021	Baden LR, El Sahly HM, Essink B, Kotloff K, Frey S, Novak R, et al. Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine. N Engl J Med. 2020 Dec 30 [Epub ahead of print]. Available from: https://doi.org/10.1056/NEJMoa2035389	The authors report interim findings of a phase-3 randomized, stratified, observer-blinded placebo-controlled trial to evaluate the efficacy and safety of the Moderna mRNA-1273 COVID-19 vaccine.	Review of “Efficacy and safety of mRNA-1273 SARS-CoV-2 vaccine”
January 8, 2021	Volz E, Mishra S, Chand M, Barrett JC, Johnson R, Geidelberg L, et al. Transmission of SARS-CoV-2 lineage B.1.1.7 in England: insights from linking epidemiological and genetic data. medRxiv 20249034 [Preprint]. 2021 Jan 04 [cited 2021 Jan 04]. Available from: https://doi.org/10.1101/2020.12.30.20249034	The SARS-CoV-2 lineage B.1.1.7 is now designated Variant of Concern 202012/01 (VOC) by Public Health England and is a genetic variant that includes amino acid substitutions that have implications related to increased ACE2 binding, and deletions that has impact on diagnostic assays.	Review of “Transmission of SARS-CoV-2 Lineage B.1.1.7 in England: Insights from Linking Epidemiological and Genetic Data”
December 24, 2020	Polack FP, Thomas SJ, Kitchin N, Absalon J, Gurtman A, Lockhart S, et al. Safety and efficacy of the BNT162b2 mRNA COVID-19 vaccine. N Engl J Med. 2020 Dec 10 [Epub ahead of print]. Available from: https://doi.org/10.1056/NEJMoa2034577	This is a report of the safety and efficacy findings from the phase 2/3 part of an ongoing multinational, randomized placebo-controlled, double-blind trial of the BNT162b2 vaccine in preventing symptomatic COVID-19 in persons 16 years of age or older after two doses (30 μg each) at 21 days apart.	Review of “Safety and Efficacy of the BNT162b2 mRNA COVID-19 Vaccine”
December 24, 2020	Voysey M, Clemens SAC, Madhi SA, Weckx LY, Folegatti PM, Aley PK, et al. Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK. Lancet. 2020 Dec 08 [Epub ahead of print]. Available from: https://doi.org/10.1016/S0140-6736(20)32661-1	The ChAdOx1 nCoV-19 vaccine was developed at Oxford University using a replication-deficient chimpanzee adenovirus vector containing the SARS-CoV-2 structural surface glycoprotein antigen (Spike protein) gene.	Review of “Safety and Efficacy of the ChAdOx1 nCoV-19 Vaccine (AZD1222) Against SARS-CoV2: An Interim Analysis of Four Randomised Controlled Trials in Brazil, South Africa, and the UK”
December 9, 2020	Article 1. Ioannidis JPA, Axfors C, Contopoulos-Ioannidis DG. Population-level COVID-19 mortality risk for non-elderly individuals overall and for non-elderly individuals without underlying diseases in pandemic epicenters. Environ Res. 2020 Jul 01 [Epub ahead of print]. Available from: https://doi.org/10.1016/j.envres.2020.109890 Article 2. Ioannidis JPA. Infection fatality rate of COVID-19 inferred from seroprevalence data. Bulletin of the World Health Organization. 2020 Oct 14 [Epub ahead of print]. Available from: https://www.who.int/bulletin/online_first/BLT.20.265892.pdf	COVID-19 infection fatality rates reported in two studies by Ioannidis et al. One cross-sectional study reports COVID death data from European, Canadian and US locations; the second reviews seroprevalence and mortality data of COVID-19 from 51 locations. Both articles are in the context of wave one of the pandemic.	COVID-19 Infection Fatality Rates Reported in Two Studies by Ioannidis et al.
December 4, 2020	Aydillo T, Gonzalez-Reiche AS, Aslam F, van de Guchte A, Khan Z, Obla A, et al. Shedding of viable SARS-CoV-2 after immunosuppressive therapy for cancer. N Engl J Med. 2020 Dec 1 [Epub ahead of print]. Available from: https://www.nejm.org/doi/10.1056/NEJMc2031670	This study investigated the shedding of live severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 20 patients with cancer and immune system compromise. Patients were from a single cancer centre in New York City and diagnosed with Coronavirus Disease 2019 (COVID-19) between March 10 and April 20, 2020.	Review of “Shedding of viable SARS-CoV-2 after immunosuppressive therapy for cancer”
December 1, 2020	Bundgaard H, Bundgaard JS, Raaschou-Pedersen DET, von Buchwald C, Todsen T, Norsk JB, et al. Effectiveness of adding a mask recommendation to other public health measures to prevent SARS-CoV-2 infection in Danish mask wearers. Ann Intern Med. 2020 Nov 18 [Epub ahead of print]. Available from: https://doi.org/10.7326/M20-6817	This is a community-based unblinded randomized controlled trial in five regions in Denmark between April 3 and June 2, 2020 to assess if recommendations for wearing surgical masks outside the home would protect wearers from acquiring coronavirus disease 2019 (COVID-19).	Review of “Effectiveness of Adding a Mask Recommendation to Other Public Health Measures to Prevent SARS-CoV-2 Infection in Danish Mask Wearers”
December 30, 2020	Hobbs CV, Martin LM, Kim SS, Kirmse BM, Haynie L, McGraw S, et al. Factors associated with positive SARS-CoV-2 test results in outpatient health facilities and emergency departments among children and adolescents aged <18 years—Mississippi, September–November 2020. MMWR Morb Mortal Wkly Rep. 2020;(69)50:1925-9. Available from: https://doi.org/10.15585/mmwr.mm6950e3	This is a case-control study that compares school, community, and close contact exposures of persons aged <18 years who tested positive for COVID-19 by reverse transcription–polymerase chain reaction (RT-PCR) (case patients), with those who tested negative (control participants).	Review of “Factors associated with positive SARS-CoV-2 test results in outpatient health facilities and emergency departments among children and adolescents aged <18 years—Mississippi, September–November 2020”
November 19, 2020	Chang S, Pierson E, Koh PW, Gerardin J, Redbird B, Grusky D, et al. Mobility network models of COVID-19 explain inequities and inform reopening. Nature. 2020 Nov 10 [Epub ahead of print] Available from: https://doi.org/10.1038/s41586-020-2923-3	Integrating mobility networks data into the SEIR epidemiological model, the authors compared the estimated risks of infection with full reopening of non-residential points of interest (POIs) frequented by people, with stringent reopening by restricting peak occupancy at certain POIs, and identified populations at risk of COVID-19 infection.	Review of “Mobility network models of COVID-19 explain inequities and inform reopening”
November 3, 2020	Pan American Health Organization/World Health Organization. Interim guidelines for detecting cases of reinfection by SARS-CoV-2. 27 October 2020. Washington, DC: Pan American Health Organization/World Health Organization; 2020. Available from: https://www.paho.org/en/documents/interim-guidelines-detecting-cases-reinfection-sars-cov-2	This Pan American Health Organization (PAHO) document proposes interim case definitions for detecting and documenting reinfection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).	Review of “Interim Guidelines for Detecting Cases of Reinfection by SARS-CoV-2”
October 28, 2020	National Academies of Sciences, Engineering, and Medicine 2020. Airborne transmission of SARS-CoV-2: proceedings of a workshop in brief. Washington, DC: The Academies Press. 2020. Available from: https://doi.org/10.17226/25958	The report is a high-level summary of the presentations and discussions at a workshop on airborne transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) held in August, 2020. This report summarizes views of individual experts and is not meant to represent consensus conclusions or recommendations.	Review of “Airborne Transmission of SARS-CoV-2: Proceedings of a Workshop in Brief”
October 28, 2020	Hale T, Phillips T, Petherick A, Kira B, Angrist N, Aymar K, et al. Risk of openness index: when do government responses need to be increased or maintained? Oxford, United Kingdom: Blavatnik School of Government Research Note. 2020 Sept 3 [cited 2020 Oct 20]. Available from: https://www.bsg.ox.ac.uk/research/publications/risk-openness-index-when-do-government-responses-need-be-increased-or	The Risk of Openness Index (RoOI), previously Lockdown Rollback Checklist, is a dataset of risk ratings (risk of openness) that relates to a country’s readiness for adopting an ‘open’ policy (removal/reduction public health measures).	Review of “Risk of Openness Index: When do government responses need to be increased or maintained”
October 27, 2020	Pringle JC, Leikauskas J, Ransom-Kelley S, Webster B, Santos S, Fox H, et al. COVID-19 in a correctional facility employee following multiple brief exposures to person with COVID-19 – Vermont, July-August 2020. MMWR. 2020;69. Available from: https://www.cdc.gov/mmwr/volumes/69/wr/pdfs/mm6943e1-H.pdf	A correctional officer assigned to an 8-hour shift in a correctional facility quarantine unit on July 28, 2020 containing six SARS-CoV-2 positive, asymptomatic detained persons became symptomatic one week later with a subsequent positive polymerase chain reaction (PCR) test result.	Review of “COVID-19 in a correctional facility employee following multiple brief exposures to person with COVID-19 – Vermont, July-August 2020”
October 21, 2020	Riddell S, Goldie S, Hill A, Eagles D, Drew TW. The effect of temperature on persistence of SARS-CoV-2 on common surfaces. Virol J. 2020 Oct 7 [Epub ahead of print]. Available from: https://doi.org/10.1186/s12985-020-01418-7	The authors tested the stability of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) under controlled conditions on six surface types.	Review of “The effect of temperature on persistence of SARS-CoV-2 on common surfaces”
October 15, 2020	Asadi S, Cappa CD, Barreda S, Wexler AS, Bouvier NM, Ristenpart WD. Efficacy of masks and face coverings in controlling outward aerosol particle emission from expiratory activities. Sci Rep. 2020 Sep 24 [Epub ahead of print]. Available from: https://doi.org/10.1038/s41598-020-72798-7	This report examines the efficacy of 6 types of masks and respirators at reducing outward aerosol emission from breathing, speaking, coughing and jaw moving.	Review of “Efficacy of face masks and face coverings in controlling outward aerosol particle emission from expiratory activities”
September 18, 2020	Doung-ngern P, Suphanchaimat R, Panjangampatthana A, Janekrongtham C, Ruampoom D, Daochaeng N, et al. Case-control study of use of personal protective measures and risk for SARS-CoV-2 infection, Thailand. Emerg Infect Dis. 2020 Sep 14 [Epud ahead of print]. Available from: https://doi.org/10.3201/eid2611.203003	This is a retrospective case-control study to evaluate the effectiveness of mask wearing, hand washing, social distancing and other personal protective measures in preventing Coronavirus Disease 2019 (COVID-19) infection in public venues in Thailand.	Review of “Case-control study of use of personal protective measures and risk for severe acute respiratory syndrome coronavirus 2 infection, Thailand”
September 15, 2020	Leclerc QJ, Fuller NM, Knight LE, Funk S, Knight GM, CMMID COVID-19 Working Group. What settings have been linked to SARS-CoV-2 transmission clusters?. Wellcome Open Res. 2020; 5(83):83. [Epub ahead of print]. Available from: https://doi.org/10.12688/wellcomeopenres.15889.2	This paper is a systematic review to determine the types of indoor and outdoor settings where transmission and clusters of COVID-19 have been reported.	Review of “What settings have been linked to SARS-CoV-2 transmission clusters?”
September 8, 2020	Kang M, Wei J, Yuan J, Guo J, Zhang Y, Hang J, et al. Probable evidence of fecal aerosol transmission of SARS-CoV-2 in a high-rise building. Ann Intern Med. 2020 Sep 01 [Epub ahead of print]. Available from: https://doi.org/10.7326/m20-0928	This study investigated an outbreak of nine COVID-19 cases in a high-rise apartment building in Guangzhou, China (January 26 to February 13, 2020), where the potential mode of transmission was through fecal aerosols.	Review of “Probable evidence of fecal aerosol transmission of SARS-CoV-2 in a high-rise building”
September 8, 2020	Gudbjartsson DF, Norddahl GL, Melsted P, Gunnarsdottir K, Holm H, Eythorsson E, et al. Humoral immune response to SARS-CoV-2 in Iceland. New Engl J Med. 2020 Sep 1 [Epub ahead of print]. Available from: https://doi.org/10.1056/NEJMoa2026116	The authors assessed Coronavirus Disease 2019 (COVID-19) seroprevalence among 30,576 Iceland residents.	Review of “Humoral immune response to SARS-CoV-2 in Iceland”
August 31, 2020	To KK-W, Hung IF-N, Ip JP, Chu AW-H, Chan W-M, Tam AR, et al. COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing. Clin Infect Dis. 2020 Aug 25 [Epub ahead of print]. Available from: https://doi.org/10.1093/cid/ciaa1275	This study documents Coronavirus Disease 2019 (COVID-19) reinfection in a 33-year-old male resident of Hong Kong 142 days after the first episode.	Review of “COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing”
July 17, 2020	Morawska L, Milton DK. It is time to address airborne transmission of COVID-19. Clin Infect Dis. 2020 Jul 6 [Epub ahead of print]. Available from: https://doi.org/10.1093/cid/ciaa939	The authors appeal to relevant national and international organizations and the medical community to recognize the risk of airborne transmission of Coronavirus Disease 2019 (COVID-19).	Review of “It is time to address airborne transmission of COVID-19”
June 29, 2020	Mitze T, Kosfeld R, Rode J, Wälde K. Face masks considerably reduce COVID-19 cases in Germany: a synthetic control method approach. IZA Discussion Paper Series No. 13319. Bonn, Germany: IZA Institute of Labour Econoimics; 2020. Available from: https://www.iza.org/publications/dp/13319/face-masks-considerably-reduce-covid-19-cases-in-germany-a-synthetic-control-method-approach	This study used a synthetic control method (SCM) to assess the effect of face mask use on the spread of Coronavirus Disease 2019 (COVID-19) in Germany.	Review of “Face masks considerably reduce COVID-19 cases in Germany: a synthetic control method approach”
June 20, 2020	Kucharski AJ, Klepac P, Conlan AJK, Kissler SM, Tang ML, Fry H, et al. Effectiveness of isolation, testing, contact tracing, and physical distancing on reducing transmission of SARS-CoV-2 in different settings: a mathematical modelling study. Lancet Infect Dis. 2020 Jun 16 [Epub ahead of print]. Available from: https://doi.org/10.1016/S1473-3099(20)30457-6	This modelling study estimated the reduction of Coronavirus Disease 2019 (COVID-19) transmission under different public health strategies and settings, and estimated the number of contacts that would need to be quarantined under different strategies.	Review of “Effectiveness of isolation, testing, contact tracing, and physical distancing on reducing transmission of SARS-CoV-2 in different settings: a mathematical modelling study”
June 16, 2020	World Health Organization. Advice on the use of masks in the context of COVID-19. Interim guidance. 5 June 2020 [Internet]. Geneva: World Health Organization; 2020. Available from: https://apps.who.int/iris/rest/bitstreams/1279750/retrieve	This is an update of interim guidance from the WHO on the use of masks in the context of COVID-19.	Review of “Advice on the use of masks in the context of COVID-19: interim guidance -5 June 2020”
June 10, 2020	Flaxman S, Mishra S, Gandy A, Unwin HJT, Mellan TA, Coupland H, et al. Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe. Nature. 2020 Jun 8 [Epub ahead of print]. Available from: https://doi.org/10.1038/s41586-020-2405-7	The authors modelled and assessed the impact of non-pharmaceutical interventions (NPIs) on Coronavirus Disease 2019 (COVID-19) transmission in 11 European countries (Austria, Belgium, Denmark, France, Germany, Italy, Norway, Spain, Sweden, Switzerland, United Kingdom).	Review of “Estimating the effects of non-pharmaceuticalinterventions on COVID-19 in Europe”
June 8, 2020	Block P, Hoffman M, Raabe IJ, Dowd JB, Rahal C, Kashyap R, et al. Social network-based distancing strategies to flatten the COVID-19 curve in a post-lockdown world. Nature Hum Behav. 2020 Jun 4 [Epub ahead of print]. Available from: https://doi.org/10.1038/s41562-020-0898-6	This study adopts a social network approach to evaluate the effectiveness of three distancing strategies designed to keep the curve flat and aid compliance in a post-lockdown world: limiting interaction to a few repeated contacts, seeking similarity across contacts and strengthening communities via triadic strategies.	Review of “Social network-based distancing strategies to flatten the COVID-19 curve in a post-lockdown world”
June, 4, 2020	Chu DK, Akl EA, Duda S, Solo K, Yaacoub S, Schünemann HJ, et al. Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis. Lancet. 2020 Jun 1 [Epub ahead of print]. Available from: https://doi.org/10.1016/S0140-6736(20)31142-9	This is a systematic review and meta-analysis of observational studies on the protective effectiveness of physical distancing, face masks and eye protection from infection from Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS) or Coronavirus Disease 2019 (COVID-19).	Review of “Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis”
May 28, 2020	Skowronski DM, Zou M, Clarke Q, Chambers C, Dickinson JA, Sabaiduc S, et al. Influenza vaccine does not increase the risk of coronavirus or other non-influenza respiratory viruses: retrospective analysis from Canada, 2010-11 to 2016-17. Clin Infect Dis. 2020 Available from: https://doi.org/10.1093/cid/ciaa626	This study addresses the hypothesis that influenza vaccination may increase the risk of Coronavirus Disease 2019 (COVID-19) by examining the relationship between influenza vaccination and the risk of non-influenza respiratory viruses (NIRV), including seasonal coronaviruses, in Canada from the 2010-11 season through the 2016-17 season.	Review of “Influenza vaccine does not increase the risk of coronavirus or other non-influenza respiratory viruses: retrospective analysis from Canada, 2010-11 to 2016-17”
May 24, 2020	Chandrashekar A, Liu J, Martinot AJ, McMahan K, Mercado ND, Peter L, et al. SARS-CoV-2 infection protects against rechallenge in rhesus macaques. Science. 2020 May 20 [Epub ahead of print]. Available from: https://doi.org/10.1126/science.abc4776	Using a rhesus macaque model of coronavirus disease 2019 (COVID-19), the authors explored whether primary infection induces a humoral and cellular immune response protective against reinfection.	Review of “SARS-CoV-2 infection protects against rechallenge in rhesus macaques”
May 22, 2020	Sood N, Simon P, Ebner P, Eichner D, Reynolds J, Bendavid E, et al. Seroprevalence of SARS-CoV-2-specific antibodies among adults in Los Angeles County, California, on April 10-11, 2020. JAMA. 2020 May 18 [Epub ahead of print]. Available from: https://doi.org/10.1001/jama.2020.8279	This study uses antibody (Ab) testing to determine the point seroprevalence of COVID-19-specific Ab in Los Angeles County, California from April 10-14, 2020.	Review of “Seroprevalence of SARS-CoV-2-specific antibodies among adults in Los Angeles County, California, on April 10- 11, 2020”
May 17, 2020	DeBiasi RL, Song X, Delaney M, Bell M, Smith K, Pershad J, et al. Severe COVID-19 in children and young adults in the Washington, DC metropolitan region. J Pediatr. 2020 May 13 [Epub ahead of print]. Available from: https://dx.doi.org/10.1016/j.jpeds.2020.05.007	Medical records of 177 children and young adults with coronavirus disease 2019 (COVID-19) treated between Mar 15–Apr 30, 2020 at a medical centre in Washington, DC were retrospectively reviewed to determine any association between specific epidemiologic and clinical features with hospitalization and/or critical care.	Review of “Severe COVID-19 in children and young adults in the Washington, DC metropolitan region”
May 15, 2020	Verdoni L, Mazza A, Gervasoni A, Martelli L, Ruggeri M, Ciuffreda M, et al. An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. Lancet. 2020 May 13 [Epub ahead of print]. Available from: https://doi.org/10.1016/S0140-6736(20)31103-X	This study describes the clinical characteristics of Kawasaki-like disease in patients before (Group 1: January 1, 2015 to February 17, 2020) and during (Group 2: February 18, 2020 to April 20, 2020) the Coronavirus Disease 2019 (COVID-19) epidemic in Bergamo, Italy.	Review of “An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study”

Sujets émergents : synopsis des principaux articles de recherche sur la COVID-19

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