Human Papilloma Virus – HPV – Biopsy

Testing Indications

The Human Papilloma Virus (HPV) may be visualized by electron microscopy (EM), however this test has very low sensitivity. The preferred method for HPV detection involves molecular testing and immunohistochemistry. PHO does not perform molecular testing for HPV. If molecular testing is preferred, contact your local private community laboratory. If EM is preferred, refer to the following information.

Specimen Collection and Handling

Specimen Requirements

Test Requested Required Requisition(s) Specimen Type Minimum Volume Collection Kit

Human Papilloma Virus (HPV)

Scrapings from skin lesions, skin crust and wart

Scrapings from skin lesions, skin crust and wart

Limitations

Although the Human Papilloma virus may be visualized by electron microscopy (EM), this test has very low sensitivity. The preferred method for HPV detection involves molecular testing and immunohistochemistry.

If molecular testing is preferred, contact your local private community laboratory.

Preparation Prior to Transport

Label the specimen with the patient’s full name, date of collection and one other unique identifier such as the patient’s date of birth or Health Card Number. Failure to provide this information may result in rejection or testing delay.

Special Instructions

Requisitions and Kit Ordering

Test Frequency and Turnaround Time (TAT)

EM is performed daily Monday to Friday.

TAT is up to 3 days from receipt by PHO laboratory.

Reporting

Results are reported to the ordering physician or health care provider as indicated on the requisition.

Test Methods

The Human Papilloma virus is detected using electron microscopy (EM).

Additional Information

SeeClinician Fact Sheet from Cancer Care Ontario.

Mis à jour le 28 mars 2019