Détails des événements

PHO Rounds: Preventing Childhood Asthma: The Neglected Impacts of Antibiotic Stewardship and Human Milk Exposure in Infants

Asthma is the most prevalent chronic disease of childhood in high-income countries. The epidemic grew rapidly in the late 20th century but there are now signs of declining incidence and prevalence in several countries. Early infancy is a key period for immune system development under the influence of genetics, host biology and environment, including the developing gut microbiota. A recent meta-analysis concludes a roughly doubled risk of asthma for children who receive antibiotics in infancy and other studies show that, breast feeding was found to substantially mitigate antibiotic-associated disruption of microbiota and asthma risk. This session of PHO Rounds presents a recently concluded study of 600,000 Canadian children in two provinces, showing that this association is operating in populations at a scale that may help to explain observed tempering of the asthma epidemic. We will address important critiques of this hypothesis and conclude with a discussion of next steps for research and possible implications for clinical and public health practice.

Intended audience: Presentation will be of interest to practitioners of public health, pediatricians, infectious diseases specialists and microbiologists, and those interested in population-based cohort design.

By the end of this session, participants will be able to:

• Describe recent changes in childhood asthma epidemiology, including possible explanations and correlation with changing antibiotic use in infancy
• Recognize current evidence linking perturbation of the developing infant gut microbiota and subsequent experience of atopic disease
• Summarize studies to date and describe published findings from the Canadian Healthy Infant Longitudinal Development Study and a cohort study of 600,000 Canadian children from BC and Manitoba
• Discuss current implications, knowledge gaps and future research in the field of childhood asthma

Présentateur(s): Dr. David Patrick

Dr. David Patrick is an infectious diseases specialist and epidemiologist with a career interest in responding to emerging infectious diseases. He is a Professor in the School of Population and Public Health at UBC and has also served as Director there, as well as a Research Director at the British Columbia Centre for Disease Control. He has published over 250 papers and books on topics ranging from HIV to COVID-19. His main research focuses on containing the threat of antimicrobial resistance and understanding the connection between antibiotic use and atopic disease at the population level.

Avis de non-responsabilité

The opinions expressed by speakers and moderators do not necessarily reflect the official policies or views of Public Health Ontario, nor does the mention of trade names, commercial practices, or organizations imply endorsement by Public Health Ontario.

Accréditation

Public Health Ontario Grand Rounds are a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada (RCPSC). In order to receive written documentation for Continuing Medical Education (CME) credits, please check “Yes” beside the question “Do you require CME credits?” on the registration form.

College of Family Physicians of Canada (CFPC) Affiliate Members may count RCPSC credits toward their Mainpro+ credit requirements. All other CFPC members may claim up to 50 Certified credits per cycle for participation in RCPSC MOC Section 1 accredited activities.

PHO Grand Rounds are also approved by the Council of Professional Experience for professional development hours (PDHs) for members of the Canadian Institute of Public Health Inspectors (CIPHI).

For more information or for a record of registration for other Continuing Education purposes, please contact events@oahpp.ca

Accessibilité

Public Health Ontario is committed to complying with the Accessibility for Ontarians with Disabilities Act (AODA). If you require accommodations to participate in this event, please contact 647-260-7100 or events@oahpp.ca.