Event Details

HIV pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) are safe and effective biomedical prevention strategies and are key to ending the HIV epidemic as a public health threat by 2030. On December 1, 2025, in commemoration of World AIDS Day, a working group of the CIHR Pan-Canadian Network for HIV/STBBI Clinical Trials Research (CTN+) published an update to Canadian clinical guidelines on PrEP/PEP in the Canadian Medical Association Journal. The guideline was developed by a diverse panel that conducted preliminary community consultations, performed systematic reviews of published literature, deliberated on the data using a rigorous evidence-to-decision framework, and ultimately formulated recommendations using the GRADE methodology. Key topics covered include who to prescribe PrEP and PEP to, which regimens to prescribe, and how to provide counseling, monitoring and follow-up. This session will review key takeaways from the guideline for clinicians, and may also be of interest to public health officials/community representatives.

Intended Audience:
Public health clinicians, Public Health professionals who work in sexual health, community health care workers, program staff involved in STBBI prevention initiatives, pharmacists, researchers working in STBBIs or HIV prevention.

By the end of this event, participants will be able to:

• Describe recent epidemiologic trends in first-time HIV diagnoses and uptake of HIV PrEP in Ontario.
• Describe the current Canadian guideline recommendations for identifying individuals who are appropriate candidates for HIV PrEP and PEP.
• Identify evidence‑based antiretroviral regimens for HIV PrEP and PEP in clinical practice.
• Identify and access accredited, self‑directed online educational resources to further support ongoing learning about PrEP and PEP.

Maria Victoria Dreher Wentz, MSc, is an epidemiologist at the Ontario HIV Treatment Network (OHTN) working in HIV epidemiology and surveillance. She completed a Master’s degree in Control of Infectious Diseases at the London School of Hygiene & Tropical Medicine (LSHTM). In her current role, she supports the Ontario HIV Epidemiology and Surveillance Initiative (OHESI) in collaboration with public health and government partners through data quality assurance, analysis, and reporting. She also leads Ontario’s HIV PrEP surveillance, monitoring PrEP uptake and trends across the province.

Darrell H. S. Tan, MD, FRCPC, PhD, is an Associate Professor in the Department of Medicine and Institute of Health Policy, Management and Evaluation at the University of Toronto. He is an infectious diseases physician and Clinician-Scientist at St. Michael’s Hospital, where he leads the Options Collaboratory in HIV/STI Treatment and Prevention Science (www.optionslab.ca). His research focuses on clinical trials and implementation science in the areas of HIV prevention and treatment, and sexually transmitted infections (STIs). Dr. Tan holds a Tier 2 Canada Research Chair in HIV Prevention and STIs, co-leads the CTN+ Prevention & Testing Think Tank, and is a member of the Governing Council of the International AIDS Society.

The opinions expressed by speakers and moderators do not necessarily reflect the official policies or views of Public Health Ontario, nor does the mention of trade names, commercial practices, or organizations imply endorsement by Public Health Ontario.

Public Health Ontario Rounds are a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada (RCPSC).

Other colleges, including the College of Family Physicians of Canada, Royal College of Dental Surgeons of Ontario and the Canadian Institute of Public Health Inspectors, may accept RCPSC accredited events on a per-hour basis. Please contact your relevant college should you have any questions.

In order to receive written documentation for Continuing Medical Education (CME) credits, please check "Yes" beside the question "Do you require CME credits?" on the registration form.

For more information or for a record of registration for other Continuing Education purposes, please contact capacitybuilding@oahpp.ca.

Public Health Ontario is committed to complying with the Accessibility for Ontarians with Disabilities Act (AODA). If you require accommodations to participate in this event, please contact 647-260-7100 or capacitybuilding@oahpp.ca.